Scientist II, HybridomaPosted: November 22, 2009
Located in New York City, NY, this is a biopharmaceutical company dedicated to developing breakthrough biologic medicines in the area of oncology. The Company has utilized the many advances made in the fields of molecular biology, oncology, genomics, and antibody engineering to build a novel pipeline of product candidates designed to address specific genetic mechanisms involved in cancer growth and development.
Their goal is to become a fully-integrated biopharmaceutical company that has the capability and resources to take its novel pipeline compounds and develop them from the research and development stage through to commercial manufacture, marketing and sales. With their first innovative cancer drug on the market and late stage clinical candidates soon to be, they have cooperative agreements with several big pharmaceutical companies to help market their drugs. A solid, fast growing midsized company which incorporates the best of both worlds, security with room to grow.
Currently looking for a Scientist II (Hybridoma)
GENERAL SUMMARY
The candidate will be working with a group on the development of therapeutic antibodies in oncology using hybridoma technology. Requirements include Ph.D. 2+, or BS/MS 6+ years of experience in immunology and tumor biology in industrial or academic settings. The individual must have proficient knowledge and expertise in hybridoma antibody generation. The individual will be accountable for implementing all tasks of hybridoma techniques to completion of establishment of monoclonal hybridoma cell lines producing antibodies of interests. The individual will have responsibilities for developing assays suitable for identification of antibodies to specific targets, and performing immunochemical and cell-based assays for validation of antibody activity and studies on advancing antibody development platform. Experience in molecular biology and B cell immune response is a plus. The qualified candidate must be a highly motivated individual with proven skills in verbal and written communication and teamwork.
ESSENTIAL DUTIES AND RESPONSIBILITIES
1. Generation of antibodies to various molecules using hybridoma technology.
2. Co-ordinate with project teams to streamline the antibody generation process.
3. Development of immunochemistry and cell-based assays for validation of antibody activity.
4. Performance of studies with candidate antibodies in biological assays.
5. Fully document all protocols and results in notebook and compose summary report.
ESSENTIAL KNOWLEDGE, SKILLS, EXPERIENCE
1. Knowledge and expertise in hybridoma antibody generation.
2. Proven hands-on skills in the performance of ELISA, FACS, Western-blot, PCR, cDNA cloning.
3. Knowledge and research experience in immunology and tumor biology.
4. Experience and skills in performing studies on B cell immune response and function.
5. Strong organization and communication skill, and ability to work within a team environment. Please refer to job code CMS 106239 when responding to this ad.
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