Process Development Scientist - Cell CulturePosted: November 6, 2009
Process Development Scientist- Cell Culture DMS 21535 COMPANY: Located in central NJ, this is a biopharmaceutical company dedicated to developing breakthrough biologic medicines in the area of oncology. The Company has utilized the many advances made in the fields of molecular biology, oncology, genomics, and antibody engineering to build a novel pipeline of product candidates designed to address specific genetic mechanisms involved in cancer growth and development. Their goal is to become a fully-integrated biopharmaceutical company that has the capability and resources to take its novel pipeline compounds and develop them from the research and development stage through to commercial manufacture, marketing and sales. With their first innovative cancer drug on the market and late stage clinical candidates soon to be, they have cooperative agreements with several big pharmaceutical companies to help market their drugs. A solid, fast growing midsized company which incorporates the best of both worlds, security with room to grow. LOCATION: Central NJ DESCRIPTION: A working knowledge of cell culture techniques, process and media optimization, bench scale bioreactor operations, scale-up and process transfer. Position requires the ability to develop production processes for proteins that are intended for human use. Familiarity of cGMPs in terms of practice and documentation is essential. The ability to interact and convey ideas in a way that ensures good process transfer to Manufacturing groups within the company or outside CMOs . Ability to develop analytical approaches that aid in the development of an optimized production process is a plus. Able to interact with junior members of the group in planning daily activities. Position requires the ability to trouble shoot and work independently to resolve any problems that might occur. Development of production process for proteins using bench scale bioreactors or other models. Ability to analyze data, interpret results and draw conclusions from process related experiments. Scale-up of bench scale production processes and process transfer. Process optimization in bench scale bioreactors for various key process parameters. Maintains laboratory notebook. Writing of SOPs, development reports and supporting documentation. Maintain high level of scientific knowledge by attending seminars, conferences etc. Technical involvement with validation studies (i.e. range evaluation studies). Ability to plan experiments that effectively move projects along. Responsible for planning day-to-day activities of Junior Staff members. EXPERIENCE: Requires a B.S. and a minimum of 5-7 years or an M.S. and a minimum of 3-5 years in depth knowledge and prior experience with aseptic cell culture techniques, small-scale cell culture process development and hands-on bioreactor operations including scale-down model systems is required A good working knowledge or prior use of statistical design of experiments (DOE) is desired. Ability to manage several different projects and good communication skills. EDUCATION: Requires a B.S. and a minimum of 5-7 years or an M.S. and a minimum of 3-5 years Please refer to job code DMS 21535 when responding to this ad.
|
