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  Bristol Myers Squibb

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Sr Principal Veterinary Pathologist

Posted:  October 30, 2009

Title: Sr Principal Veterinary Pathologist Location: NJ-New Brunswick Has strong comparative pathology and veterinary medical/scientific skills, including the ability to identify and apply new scientific ideas and technologies. Performs gross and microscopic examinations of animal tissues in toxicity and/or efficacy studies (anatomic pathologists only). Interprets and investigates the significance of results of clinical pathology, organ weight, necropsy, and/or histopathology data from toxicology studies. Contributes to and/or generates pathology reports that accurately and completely reflect the data collected and the significance of the data to drug registration and safety. Reviews study protocols and provides input into the design of the clinical pathology and/or anatomic pathology portions of the protocols. Supervises necropsies (anatomic pathologists only). Conducts pathology peer reviews. Is well organized with good management skills (project, time, or people). Has very good oral and written communication skills and the ability to clearly present complex ideas and concepts. Is proactive and has strong scientific and problem-solving skills; ability to interpret and integrate diverse data types. Has strong interpersonal skills with an ability to collaborate and work effectively in cross-functional teams, particularly in the face of conflicting priorities and difficult situations. Ensures compliance with GLPs, SOPs, safety, and animal welfare guidelines and state and federal regulations applicable to functional area or laboratory. Supports drug discovery and development in the selection and advancement of drug candidates to clinical development. Provides technical and/or scientific leadership in the selection, evaluation, and application of potential biomarkers of efficacy and/or toxicity. Provides consultation on unusual or complex anatomic or clinical pathology findings. Provides consultation on interpretation of cytology, bone marrow aspirates, CSF taps, urine sediment, etc. (clinical pathologists). Trains and supervises medial technologists (clinical pathologists), necropsy/histology technicians (anatomic pathologists), and specialized technicians in new laboratory procedures and investigative methodologies. May oversee the operation of a specific laboratory or function within the DSPCO clinical and anatomic pathology organization. Participate in multifunctional toxicology issue response teams. Makes presentations at scientific meetings and publishes in peer-reviewed scientific journals. Represents DSPCO on Discovery Working Groups, Early Development Teams, and/or Full Development Teams. Has ability to interpret diverse data sets and use scientific expertise to impact issue resolution and influence discovery or development programs. Has ability to readily internalize or clearly communicate enabling strategies that align people, resources, and activities with departmental and divisional objectives. At least 7 years of postdoctoral combined experience in industry and academia (clinical or anatomic pathology) with experience and a demonstrated aptitude at applying his/her expertise in pathology to the process of drug safety evaluation in drug discovery or development. Experience in the conduct, evaluation, and reporting of nonclinical toxicity studies is expected for development positions in pathology. Ability to write pathology reports that accurately and succinctly describe the data and interpret its relationship to drug administration and relevance to human safety. Experience in communicating effectively with co-workers at all levels of an organization and in making scientific presentations. Experience in using routine desktop computer applications and computerized pathology data collection systems. Demonstrated ability through documented experience at managing projects independently from conception to completion. Knowledge of GLPs and animal welfare regulations is expected for pathologists working in GLP laboratories. Evidence of proactive participation and impactful contributions in cross-functional and cross-divisional teams and venues. Demonstrated experience in conducting or contributing to investigative/hypothesis-driven research including project design, implementation, data interpretation, and follow-up study design. Demonstrated technical leadership within the department. Demonstrated ability to identify and understand preclinical toxicology issues and to apply knowledge gained and expertise to issue investigation/resolution and risk assessment processes. D.V.M. or equivalent required. Post-doctoral training (M.S. or Ph.D). Diplomate, ACVP or equivalent required. Broad scientific expertise in clinical and/or anatomic pathology and comprehensive knowledge of pathophysiology and comparative disease. Technical awareness or experience in specialized clinical pathology techniques, immunohistochemistry, image analysis, electron microscopy, biomarker development, genetically modified animal markers, and/or molecular biology that are applicable to the practice of clinical or anatomic pathology. Demonstrated effectiveness in both oral and written communication of ideas and complex concepts. A broad knowledge of approaches and technologies used for target validation and compound lead optimization during early development (as related to potential toxicity issues) and the ability to identify and apply novel approaches/technologies to these processes (PCO pathologists). A good understanding of the drug discovery and/or development process as it pertains to preclinical candidate optimization and/or drug safety evaluation.


Please refer to job code bristolmyers-0900717 when responding to this ad.

Category:Biotech/Pharmaceutical
     > Animal/Veterinary
Location:New Brunswick, NJ
County:Middlesex County
ZIP Code:08901
Pay Rate:Open
Job Terms:full time
Company:Bristol Myers Squibb
Phone:email only please
Fax:email only please

 
 
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