Associate Scientist II/Scientist I

About the Organization My company shares my passion for helping to improve human health around the world." "This is My MedImmune." Those who join MedImmune feel a sense of ownership about their future. They thrive with a recognized leader in the biotechnology industry and the wholly-owned subsidiary of AstraZeneca plc. Here, you will join passionate professionals who advance science, technology and medicine to develop products designed to help people live better lives. You will excel in an environment characterized by respect, integrity and growth opportunities• that encourages both individual contribution and collaborative entrepreneurial thinking. Our products and/or product candidates are designed to address areas of need in infection, oncology, respiratory disease and inflammation, cardiovascular/gastrointestinal disease and neuroscience. Explore a MedImmune career as we strive to better more lives, more often, around the world. Description Title: Associate Scientist II/Scientist I Location: MD, Gaithersburg - Corporate Headquarters Req: 02005 Position Summary: Major Duties and Responsibilities (including supervising others): Design and perform experiments for developing robust and scalable primary recovery unit operations including cell lysis and inclusion body (IB) recovery. Candidate is expected to be the expert of primary recovery in Process Biochemistry, evaluating and applying new technologies in process development. Responsibilities may also include development and trouble shooting of chromatography and UF/DF unit operations for purification of novel molecules such as protein-drug conjugates, bi-specifics and proteins expressed in E.coli systems that require re-folding. Candidate is expected to design and execute studies to meet early stage process development objectives and timeline, as well as preparation of regulatory documents (INDs, CTAs, IMPDs). Position Requirements Special Skills/Abilities: ? Theoretical knowledge and practical experience in primary recovery process development and scale up ? Expertise in homogenization/cell disruption, depth filtration, continuous centrifugation, tangential flow filtration, IB recovery, and precipitation/flocculation ? Knowledge and hands on experience with primary recovery equipment at lab scale and large scale ? Familiarity with process modeling techniques and statistical analysis ? Experience in developing protein refold or purification process for non-Mab molecules desired ? GMP experience. Familiarity with tech transfer to pilot and commercial manufacturing desired ? Experience writing regulatory documents ? Good oral and written communication skills ? Team work and collaborative ? Supervisory experience is a plus Job Complexity: Job is complex, requiring a thorough understanding of biochemical properties of biopharmaceuticals, process development and scale up in support of product commercialization. Scientific and technical expertise in primary recovery is essential. Knowledge and experience in chromatography and filtration development is required. Supervision: Reports directly to a Principal Scientist but is expected to work independently on a day-to-day basis. May supervise B.S./M..S. scientists and engineers directly or in matrix (Supervision required, level of independence) Educational Requirements Education: M.S., Ph.D. or equivalent in chemical engineering Experience: Ph.D. with 1-3 years, M.S. with 5+ years or B.S. with 8+ years of relevant experience in biotechnology and development of biopharmaceutical products Company Info None Specified

Please refer to job code 02005 when responding to this ad.

Category:	Biotech/Pharmaceutical
	> Other Biotechnology
Location:	Gaithersburg, MD
County:	Montgomery County
ZIP Code:	20877
Pay Rate:	Open
Job Terms:	full time
Company:	MedImmune Inc.
Phone:	email only please
Fax:	email only please